L3MBTL1 Antikörper (N-Term)

Produktnummer ABIN2780244

Der Kaninchen Polyklonal anti-L3MBTL1 Antikörper (ABIN2780244) detektiert spezifisch L3MBTL1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Meerschweinchen und Hund.

Kurzübersicht für L3MBTL1 Antikörper (N-Term) (ABIN2780244)

Target: L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

Reaktivität: Human, Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser L3MBTL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-L3MBTL1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: L3MBTL Antibody - N-terminal region

Sequenz: RRREGHGTDS EMGQGPVRES QSSDPPALQF RISEYKPLNM AGVEQPPSPE

Homologie: Dog: 92%, Guinea Pig: 77%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against L3MBTL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human L3MBTL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37760-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu L3MBTL1

Target: L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

Andere Bezeichnung: L3MBTL

Hintergrund:

Background Information: L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: L(3)mbt-like 1 (Drosophila)

Alternative Symbols: L3MBTL, ZC2HC3, H-L(3)MBT, dJ138B7.3

Protein Name: Lethal(3)malignant brain tumor-like protein 1

Molekulargewicht: 86kDa

Gen-ID: 26013

NCBI Accession: NP_056293

UniProt: Q9Y468

Pathways: Chromatin Binding