MED21 Antikörper (Middle Region)

Produktnummer ABIN2780233

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MED21 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für MED21 Antikörper (Middle Region) (ABIN2780233)

Target: MED21 (Mediator Complex Subunit 21 (MED21))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MED21 Antikörper

Bindungsspezifität: Middle Region

Sequenz: DSLPSEESTA ALQAASLYKL EEENHEAATC LEDVVYRGDM LLEKIQSALA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MED21. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MED21

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 144 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MED21

Target: MED21 (Mediator Complex Subunit 21 (MED21))

Andere Bezeichnung: MED21

Hintergrund: MED21 belongs to the Mediator complex subunit 21 family. It is the component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: SRB7, SURB7
Protein Interaction Partner: MAGEB4, SSC5D, ZNF655, BLOC1S6, MED21, CDK8, MED19, MED26, UBC, HTT, FBXW7, MED11, MED8, MED28, MED29, MED18, MED4, MED16, MED6, MED13, MED12, MED24, MED17, MED14, MED22, MED1, ELAVL1, VAV2, SKP1, THRA, THRB, MED10, TP53, SREBF1, ZC3H13, ZSCAN1, PCBD2, TA
Protein Size: 144

Molekulargewicht: 15 kDa

Gen-ID: 9412

NCBI Accession: NM_004264, NP_004255

UniProt: Q13503

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha