DDX1 Antikörper (C-Term)

Produktnummer ABIN2780220

Produktdetails anti-DDX1 Antikörper

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Pferd, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SQVEPDIKVP VDEFDGKVTY GQKRAAGGGS YKGHVDILAP TVQELAALEK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DDX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DDX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 740 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DDX1

Target: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Andere Bezeichnung: DDX1 (DDX1 Produkte)

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.
Alias Symbols: DBP-RB, UKVH5d
Protein Interaction Partner: HUWE1, FUS, SUMO2, SUMO3, STAU1, UBC, SUMO1, NEDD8, Fbxl16, WWOX, ZBTB1, RPA3, RPA2, RPA1, rev, C14orf166, RTCB, RPL26L1, EIF3K, NELFB, EDC4, IGF2BP3, PDCD6, ABCF1, EIF2B2, EIF2B3, YBX3, RPL27, RFC4, RFC2, QARS, YBX1, NMT1, HNRNPM, MRE11A, KRT18, ILF2, HN
Protein Size: 740

Molekulargewicht: 81 kDa

Gen-ID: 1653

NCBI Accession: NM_004939, NP_004930

UniProt: Q92499

Pathways: Ribonucleoprotein Complex Subunit Organization