ISL2 Antikörper (C-Term)

Produktnummer ABIN2780062

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ISL2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen und Hund.Es wurde in 1 Publikation zitiert.

Kurzübersicht für ISL2 Antikörper (C-Term) (ABIN2780062)

Target: ISL2 (ISL LIM Homeobox 2 (ISL2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ISL2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: ISL2 Antibody - C-terminal region

Sequenz: VIRVWFQNKR CKDKKKSILM KQLQQQQHSD KASFQGLTGT PLVAGSPIGH

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 86%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ISL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse ISL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37377-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ISL2 Antikörper (ABIN2780062)

Svärd, Heby-Henricson, Henricson, Persson-Lek, Rozell, Lauth, Bergström, Ericson, Toftgård, Teglund: "Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway." in: Developmental cell, Vol. 10, Issue 2, pp. 187-97, (2006) (PubMed).

Details zu ISL2

Target: ISL2 (ISL LIM Homeobox 2 (ISL2))

Andere Bezeichnung: ISL2

Hintergrund:

Background Information: Isl2 specifies RGC laterality by repressing an ipsilateral pathfinding program unique to VTC RGCs and involving Zic2 and EphB1. This genetic hierarchy controls binocular vision.

Gene Name: Insulin related protein 2 (islet 2)

Alternative Symbols: isle, 3110001N10Rik

Protein Name: Insulin gene enhancer protein ISL-2

Molekulargewicht: 39kDa

Gen-ID: 104360

NCBI Accession: NP_081673

UniProt: Q9CXV0