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SRA1 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-SRA1-Antikörper wurde für WB validiert. Er ist geeignet, SRA1 in Proben von Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen und Schwein zu detektieren.
Produktnummer ABIN2780049

Kurzübersicht für SRA1 Antikörper (N-Term) (ABIN2780049)

Target

Alle SRA1 Antikörper anzeigen
SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reaktivität

Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen, Schwein

Wirt

  • 17
  • 4
Kaninchen

Klonalität

  • 17
  • 5
Polyklonal

Konjugat

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SRA1 Antikörper ist unkonjugiert

Applikation

  • 20
  • 16
  • 6
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    MMRCPAGGAE VEMAELYVKP GNKERGWNDP PQFSYGLQTQ TGGPKRTPLT

    Homologie

    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 93%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against Sra1. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide corresponding to a region of Mouse
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 220 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

    Andere Bezeichnung

    Sra1

    Hintergrund

    Sra1 is a functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Sra1 also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2).Sra1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. Sra1 may play a role in tumorigenesis.
    Alias Symbols: AA959952, SRA, STRAA1, Strra1, Sra, Srap, Straa1
    Protein Interaction Partner: CFTR, Traf6, Pus1,
    Protein Size: 220

    Molekulargewicht

    24 kDa

    Gen-ID

    24068

    NCBI Accession

    NM_025291, NP_079567

    UniProt

    Q80VJ2

    Pathways

    EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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