SRA1 Antikörper (N-Term)

Produktnummer ABIN2780049

Der Kaninchen Polyklonal anti-SRA1 Antikörper wird verwendet zum Nachweis von SRA1 in Proben von Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen und Schwein. Er wurde validiert für WB.

Kurzübersicht für SRA1 Antikörper (N-Term) (ABIN2780049)

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SRA1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MMRCPAGGAE VEMAELYVKP GNKERGWNDP PQFSYGLQTQ TGGPKRTPLT

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 93%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Sra1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 220 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SRA1

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Andere Bezeichnung: Sra1

Hintergrund: Sra1 is a functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Sra1 also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2).Sra1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. Sra1 may play a role in tumorigenesis.
Alias Symbols: AA959952, SRA, STRAA1, Strra1, Sra, Srap, Straa1
Protein Interaction Partner: CFTR, Traf6, Pus1,
Protein Size: 220

Molekulargewicht: 24 kDa

Gen-ID: 24068

NCBI Accession: NM_025291, NP_079567

UniProt: Q80VJ2

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development