YAF2 Antikörper (Middle Region)

Produktnummer ABIN2780047

Der Kaninchen Polyklonal anti-YAF2 Antikörper wird verwendet zum Nachweis von YAF2 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen und Pferd. Er wurde validiert für WB.

Kurzübersicht für YAF2 Antikörper (Middle Region) (ABIN2780047)

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YAF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-YAF2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: YAF2 Antibody - middle region

Sequenz: GDLTVIITDF KEKAKSAPAS SAAGDQHSQG SCSSDSTERG VSRSSSPRGE

Homologie: Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 80%, Mouse: 100%, Rat: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against YAF2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse YAF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8116054

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu YAF2

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Andere Bezeichnung: YAF2

Hintergrund:

Background Information: Yaf2 binds to MYC and inhibits MYC-mediated transactivation. Yaf2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. Yaf2 increases calpain 2-mediated proteolysis of YY1 in vitro. Yaf2 is a component of the E2F6.com-1 complex, a repressive complex that methylates Lys-9 of histone H3, suggesting that it is involved in chromatin-remodeling.

Gene Name: YY1 associated factor 2

Alternative Symbols: 2810021M11Rik

Protein Name: YY1-associated factor 2

Molekulargewicht: 20kDa

Gen-ID: 67057

NCBI Accession: NP_077151

UniProt: Q99LW6