RYBP Antikörper (N-Term)
Kurzübersicht für RYBP Antikörper (N-Term) (ABIN2780023)
Target
Alle RYBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- RINSQLVAQQ VAQQYATPPP PKKEKKEKVE KPDKEKPEKD KDISPSVTKK
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Homologie
- Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 92%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 75%, Zebrafish: 85%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Rybp. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Rybp
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RYBP (RING1 and YY1 Binding Protein (RYBP))
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Andere Bezeichnung
- Rybp
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Hintergrund
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Rybp inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. It may be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1 and may bind to DNA. It promotes apoptosis.
Alias Symbols: 2410018J24Rik, DEDAF, YEAF1
Protein Interaction Partner: Eed, Nanog, Pcgf1, Kdm2b, Rnf2, L3mbtl2, Pcgf6, Rybp, Pcgf2, Ring1, UBC, Tfcp2l1, Pou5f1,
Protein Size: 228 -
Molekulargewicht
- 25 kDa
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Gen-ID
- 56353
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NCBI Accession
- NM_019743, NP_062717
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UniProt
- Q8CCI5
Target
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