FIGLA Antikörper (C-Term)
Kurzübersicht für FIGLA Antikörper (C-Term) (ABIN2779982)
Target
Alle FIGLA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- SSTRELLGNA TQPTSCASGL KKEEEGPWAY AGHSEPLYSY HQSTVPETRS
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Homologie
- Mouse: 100%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against Figla. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Figla
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FIGLA (Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))
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Andere Bezeichnung
- Figla
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Hintergrund
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Figla is a germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. It plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. It is essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Figla binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
Alias Symbols: bHLHc8
Protein Size: 194 -
Molekulargewicht
- 21 kDa
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Gen-ID
- 26910
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NCBI Accession
- NM_012013, NP_036143
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UniProt
- O55208
Target
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