HIRA Antikörper (Middle Region)

Produktnummer ABIN2779934

Produktdetails anti-HIRA Antikörper

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRSRELESSS DSDEKVHLAK PSSLSKRKLE LEVETVEKKK KGRPRKDSRL

Homologie: Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 86%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Hira. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse Hira

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1015 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HIRA

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Andere Bezeichnung: Hira (HIRA Produkte)

Synonyme: HIRA antikoerper, wu:fb97b07 antikoerper, wu:fi43b08 antikoerper, si:ch211-188g24.3 antikoerper, AA138857 antikoerper, D16Ertd95e antikoerper, N28177 antikoerper, Tuple1 antikoerper, DGCR1 antikoerper, TUP1 antikoerper, TUPLE1 antikoerper, dgcr1 antikoerper, hira-A antikoerper, tup1 antikoerper, tuple1 antikoerper, homolog of histone chaperone HIRA antikoerper, histone cell cycle regulator antikoerper, histone cell cycle regulator a antikoerper, protein HIRA antikoerper, HIR histone cell cycle regulation defective homolog A (S. cerevisiae) antikoerper, HIRA antikoerper, histone cell cycle regulator S homeolog antikoerper, histone chaperone HIRA-like protein antikoerper, Tuple1/HirA antikoerper, HIRA antikoerper, hira antikoerper, LOC100052845 antikoerper, LOC100352472 antikoerper, LOC100407742 antikoerper, LOC100450459 antikoerper, LOC100467668 antikoerper, LOC100581135 antikoerper, LOC486424 antikoerper, Hira antikoerper, LOC732736 antikoerper, hira.S antikoerper

Hintergrund: Hira is required for the periodic repression of histone gene transcription during the cell cycle.Hira cooperates with ASF1A to promote replication-independent chromatin assembly.Hira is required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Alias Symbols: AA138857, D16Ertd95e, N28177, Tuple1
Protein Interaction Partner: Nanog, Creb3l4, Crem, Pou5f1, Hirip3, Pax7, Pax3, H3f3b,
Protein Size: 1015

Molekulargewicht: 112 kDa

Gen-ID: 15260

NCBI Accession: NM_010435, NP_034565

UniProt: Q61666

Pathways: Chromatin Binding