HIRA Antikörper (Middle Region)

Produktnummer ABIN2779934

Der Kaninchen Polyklonal Anti-HIRA-Antikörper wurde für WB validiert. Er ist geeignet, HIRA in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd und Kaninchen zu detektieren.

Kurzübersicht für HIRA Antikörper (Middle Region) (ABIN2779934)

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HIRA Antikörper

Bindungsspezifität: Middle Region

Sequenz: LRSRELESSS DSDEKVHLAK PSSLSKRKLE LEVETVEKKK KGRPRKDSRL

Homologie: Dog: 79%, Guinea Pig: 93%, Horse: 79%, Human: 86%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Hira. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse Hira

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1015 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HIRA

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Andere Bezeichnung: Hira

Hintergrund: Hira is required for the periodic repression of histone gene transcription during the cell cycle.Hira cooperates with ASF1A to promote replication-independent chromatin assembly.Hira is required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Alias Symbols: AA138857, D16Ertd95e, N28177, Tuple1
Protein Interaction Partner: Nanog, Creb3l4, Crem, Pou5f1, Hirip3, Pax7, Pax3, H3f3b,
Protein Size: 1015

Molekulargewicht: 112 kDa

Gen-ID: 15260

NCBI Accession: NM_010435, NP_034565

UniProt: Q61666

Pathways: Chromatin Binding