EGR1 Antikörper (N-Term)

Produktnummer ABIN2779828

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch EGR1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Schaf und Schwein.

Kurzübersicht für EGR1 Antikörper (N-Term) (ABIN2779828)

Target: EGR1 (Early Growth Response 1 (EGR1))

Reaktivität: Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Schaf, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-EGR1 Antikörper

Bindungsspezifität: N-Term

Sequenz: GTPEGSGGNS SSSTSSGGGG GGGSNSGSSA FNPQGEPSEQ PYEHLTTESF

Homologie: Cow: 92%, Dog: 75%, Horse: 85%, Mouse: 100%, Pig: 85%, Rabbit: 77%, Rat: 100%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against EGR1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse EGR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 533 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EGR1

Target: EGR1 (Early Growth Response 1 (EGR1))

Andere Bezeichnung: EGR1

Hintergrund: Early Growth Response Protein 1 (EGR1, Krox-24 protein, nerve growth factor-induced protein A, Transcription factor ETR103, Zinc finger protein 225) belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.
Alias Symbols: egr, TIS8, Zenk, Egr-1, NGFIA, Zfp-6, ETR103, Krox-1, Krox24, NGF1-A, NGFI-A, Zif268, Krox-24, A530045N19Rik
Protein Interaction Partner: Sp1, Pin1, Sf1, Pitx1, Nab2, Egr1, G3bp1, Srf, Smarca4, Elk1, Hist4h4, Nelfe, Tbp, Gtf2b, Cdk8,
Protein Size: 533

Molekulargewicht: 59 kDa

Gen-ID: 13653

NCBI Accession: NM_007913, NP_031939

UniProt: P08046

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity