EGR1 Antikörper (N-Term)

Produktnummer ABIN2779828

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EGR1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Schaf und Schwein.

Kurzübersicht für EGR1 Antikörper (N-Term) (ABIN2779828)

Target: EGR1 (Early Growth Response 1 (EGR1))

Reaktivität: Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Schaf, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-EGR1 Antikörper

Bindungsspezifität: N-Term

Sequenz: GTPEGSGGNS SSSTSSGGGG GGGSNSGSSA FNPQGEPSEQ PYEHLTTESF

Homologie: Cow: 92%, Dog: 75%, Horse: 85%, Mouse: 100%, Pig: 85%, Rabbit: 77%, Rat: 100%, Sheep: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against EGR1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse EGR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 533 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EGR1

Target: EGR1 (Early Growth Response 1 (EGR1))

Andere Bezeichnung: EGR1

Hintergrund: Early Growth Response Protein 1 (EGR1, Krox-24 protein, nerve growth factor-induced protein A, Transcription factor ETR103, Zinc finger protein 225) belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.
Alias Symbols: egr, TIS8, Zenk, Egr-1, NGFIA, Zfp-6, ETR103, Krox-1, Krox24, NGF1-A, NGFI-A, Zif268, Krox-24, A530045N19Rik
Protein Interaction Partner: Sp1, Pin1, Sf1, Pitx1, Nab2, Egr1, G3bp1, Srf, Smarca4, Elk1, Hist4h4, Nelfe, Tbp, Gtf2b, Cdk8,
Protein Size: 533

Molekulargewicht: 59 kDa

Gen-ID: 13653

NCBI Accession: NM_007913, NP_031939

UniProt: P08046

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity