Arx Antikörper (Middle Region)

Produktnummer ABIN2779819

Dieses Anti-Arx-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Arx in WB. Geeignet für Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen und Pferd. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Arx Antikörper (Middle Region) (ABIN2779819)

Target: Arx (ARX) (Aristaless Related Homeobox (ARX))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Arx Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Arx Antikörper

Bindungsspezifität: Middle Region

Sequenz: TGAEDDEEEL LEDEEDEEEE EELLEDDDEE LLEDDARALL KEPRRCSVAT

Homologie: Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 93%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse ARX

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 564 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Arx Antikörper (ABIN2779819)

Price, Yoo, Burgess, Deng, Hrachovy, Frost, Noebels et al.: "A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 27, pp. 8752-63, (2009) (PubMed).

Condomines, Hose, Rème, Requirand, Hundemer, Schoenhals, Goldschmidt, Klein: "Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 832-40, (2009) (PubMed).

Details zu Arx

Target: Arx (ARX) (Aristaless Related Homeobox (ARX))

Andere Bezeichnung: ARX

Hintergrund: ARX (Aristaless-related genes), a subset of the Paired-related homeobox genes, is a group of regulators of essential events during vertebrate embryogenesis. Arx was highly conserved between mouse and zebrafish. Studies have disclosed its neuromeric expression in the forebrain and longitudinal expression in the floor plate in mouse and zebrafish. It is also expressed in the dorsal telencephalon (presumptive cerebral cortex) of mouse embryos.
Protein Size: 564

Molekulargewicht: 58 kDa

Gen-ID: 11878

NCBI Accession: NM_007492, NP_031518

UniProt: O35085