YAF2 Antikörper (Middle Region)

Produktnummer ABIN2779796

Der Kaninchen Polyklonal anti-YAF2 Antikörper wird verwendet zum Nachweis von YAF2 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für YAF2 Antikörper (Middle Region) (ABIN2779796)

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YAF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-YAF2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: TQSKKEKKDK VEKEKSEKET TSKKNSHKKT RPRLKNVDRS SAQHLEVTVG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against YAF2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human YAF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 180 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu YAF2

Target: YAF2 (YY1 Associated Factor 2 (YAF2))

Andere Bezeichnung: YAF2

Hintergrund: YAF2 interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. YAF2 contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1.
Alias Symbols: MGC41856
Protein Interaction Partner: SETBP1, XAGE1E, RING1, RNF2, BMI1, GABPB1, CSNK2A2, UBC, CAND1, PCGF1, KDM2B, PCGF5, PCGF6, L3MBTL2, FBRS, BCORL1, BCOR, MGA, CBX3, WDR5, PCGF3, YAF2, USP7, PCGF2, TFDP1, SKP1, HDAC2, E2F6, CSNK2A1, ZFP42, YY1, MYCN,
Protein Size: 180

Molekulargewicht: 20 kDa

Gen-ID: 10138

NCBI Accession: NM_005748, NP_005739

UniProt: Q8IY57