T-Bet Antikörper (Middle Region)

Produktnummer ABIN2779750

Der Kaninchen Polyklonal Anti-T-Bet-Antikörper wurde für WB und IHC validiert. Er ist geeignet, T-Bet in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen und Meerschweinchen zu detektieren.

Kurzübersicht für T-Bet Antikörper (Middle Region) (ABIN2779750)

Target: T-Bet

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser T-Bet Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-T-Bet Antikörper

Bindungsspezifität: Middle Region

Sequenz: SIPSPPGPNC QFLGGDHYSP LLPNQYPVPS RFYPDLPGQA KDVVPQAYWL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TBX21. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX21

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 535 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu T-Bet

Target: T-Bet

Andere Bezeichnung: TBX21

Hintergrund: TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
Alias Symbols: HGNC:11599, T-PET, T-bet, TBLYM, TBET
Protein Interaction Partner: USP10, UBC, EXOC5, ZNF490, SP1, HOXC11, GATA3, EP300, CREBBP,
Protein Size: 535

Molekulargewicht: 58 kDa

Gen-ID: 30009

NCBI Accession: NM_013351, NP_037483

UniProt: Q9UL17