GATA3 Antikörper (C-Term)

Produktnummer ABIN2779713

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch GATA3 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd und Schaf und wurde in 1 Publikation erwähnt.

Kurzübersicht für GATA3 Antikörper (C-Term) (ABIN2779713)

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GATA3 Antikörper

Bindungsspezifität: C-Term

Sequenz: RNRKMSSKSK KCKKVHDSLE DFPKNSSFNP AALSRHMSSL SHISPFSHSS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GATA3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GATA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 443 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GATA3 Antikörper (ABIN2779713)

Kaminuma, Kitamura, Kitamura, Miyagishi, Taira, Yamamoto, Miura, Miyatake: "GATA-3 suppresses IFN-gamma promoter activity independently of binding to cis-regulatory elements." in: FEBS letters, Vol. 570, Issue 1-3, pp. 63-8, (2004) (PubMed).

Details zu GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Andere Bezeichnung: GATA3

Hintergrund: Trans-acting T-cell specific transcription factor GATA-3 is a member of GATA family of transcription factors that regulates development of multiple tissues. It is an important transcription factor in regulating human Th2 cell differentiation in vivo.
Alias Symbols: HDR, HDRS
Protein Interaction Partner: PSMA3, FOXP3, USP21, UBC, SPI1, BRCA1, MYB, REPIN1, SP1, TBX21, HDAC5, HDAC4, HDAC3, RARB, MDM2, BMI1, MED1, ZFPM2, SATB1, TAL1, LMO1, LMO2, ETS2, ETS1,
Protein Size: 443

Molekulargewicht: 48 kDa

Gen-ID: 2625

NCBI Accession: NM_002051, NP_002042

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation