SIRT7 Antikörper (C-Term)

Produktnummer ABIN2779623

Dieses Anti-SIRT7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SIRT7 in WB. Geeignet für Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Schwein und Meerschweinchen.

Kurzübersicht für SIRT7 Antikörper (C-Term) (ABIN2779623)

Target: SIRT7 (Sirtuin 7 (SIRT7))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SIRT7 Antikörper

Bindungsspezifität: C-Term

Sequenz: DVMRLLMAEL GLEIPAYSRW QDPIFSLATP LRAGEEGSHS RKSLCRSREE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SIRT7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 400 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SIRT7

Target: SIRT7 (Sirtuin 7 (SIRT7))

Andere Bezeichnung: SIRT7

Hintergrund: SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.
Alias Symbols: SIR2L7
Protein Interaction Partner: DDB1, VPRBP, APP, NOL6, YTHDC2, DDX31, RBM15, ANAPC1, NSD1, NOC3L, UBE2O, RBM25, CCAR2, CHD8, BEND3, PHRF1, DHX37, NUFIP2, CGN, XPO5, LRRC47, BIRC6, WDR18, THOC2, NUP107, REXO4, DDX24, XAB2, UGGT1, ZC3HAV1, YLPM1, NKRF, CCT5, SNW1, DHX30, DIS3, PUF60, COP
Protein Size: 400

Molekulargewicht: 45 kDa

Gen-ID: 51547

NCBI Accession: NM_016538, NP_057622

UniProt: Q9NRC8