PAX7 Antikörper (N-Term)

Produktnummer ABIN2779615

Der Kaninchen Polyklonal Anti-PAX7-Antikörper wurde für WB und IHC validiert. Er ist geeignet, PAX7 in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Rind (Kuh) und Kaninchen zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für PAX7 Antikörper (N-Term) (ABIN2779615)

Target: PAX7 (Paired Box 7 (PAX7))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PAX7 Antikörper

Bindungsspezifität: N-Term

Sequenz: KEEEDEADKK EDDGEKKAKH SIDGILGDKG NRLDEGSDVE SEPDLPLKRK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PAX7. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAX7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 520 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PAX7 Antikörper (ABIN2779615)

McDonald, Kunz, McLoon: "Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice." in: PLoS ONE, Vol. 9, Issue 1, pp. e86424, (2014) (PubMed).

Details zu PAX7

Target: PAX7 (Paired Box 7 (PAX7))

Andere Bezeichnung: PAX7

Hintergrund: PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.
Alias Symbols: HUP1, RMS2, PAX7B
Protein Interaction Partner: TRIM27, MYOD1, Dlg4, WDR5, ASH2L, HIRA, Ubc,
Protein Size: 520

Molekulargewicht: 57 kDa

Gen-ID: 5081

NCBI Accession: NM_002584, NP_002575

UniProt: P23759