RUVBL2 Antikörper (N-Term)
RUVBL2
Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
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- Target Alle RUVBL2 Antikörper anzeigen
- RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))
- Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae
- Wirt
- Kaninchen
- Klonalität
- Polyklonal
- Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- IERIGAHSHI RGLGLDDALE PRQASQGMVG QLAARRAAGV VLEMIREGKI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RUVBL2. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL2
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 463 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))
- Andere Bezeichnung
- RUVBL2
- Hintergrund
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RuvB-Like 2 (48- kDa TATA box-binding protein-interacting protein, Reptin 52, RUVBL2) is the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this protein has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
Alias Symbols: RVB2, TIH2, ECP51, TIP48, CGI-46, INO80J, REPTIN, TIP49B
Protein Interaction Partner: CCDC103, LNX1, RUVBL1, UBC, DPCD, HUWE1, VCP, SUMO2, RPAP3, MDM2, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, BMI1, CDKN2A, ASNA1, PPP6R3, PLA2G4A, PARK2, FBXO6, TARDBP, YWHAQ, PPP6R2, EXOSC10, BAG3, POLR2E, UPF1, SMG1, RBM8A, TTI1, PAN2, TBP, CTNNB1, STOM, RUVBL
Protein Size: 463 - Molekulargewicht
- 51 kDa
- Gen-ID
- 10856
- NCBI Accession
- NM_006666, NP_006657
- UniProt
- Q9Y230
- Pathways
- Telomere Maintenance
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