RUVBL2 Antikörper (N-Term)

Produktnummer ABIN2779600

Produktdetails anti-RUVBL2 Antikörper

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUVBL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: IERIGAHSHI RGLGLDDALE PRQASQGMVG QLAARRAAGV VLEMIREGKI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against RUVBL2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 463 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RUVBL2

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Andere Bezeichnung: RUVBL2 (RUVBL2 Produkte)

Hintergrund: RuvB-Like 2 (48- kDa TATA box-binding protein-interacting protein, Reptin 52, RUVBL2) is the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this protein has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
Alias Symbols: RVB2, TIH2, ECP51, TIP48, CGI-46, INO80J, REPTIN, TIP49B
Protein Interaction Partner: CCDC103, LNX1, RUVBL1, UBC, DPCD, HUWE1, VCP, SUMO2, RPAP3, MDM2, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, BMI1, CDKN2A, ASNA1, PPP6R3, PLA2G4A, PARK2, FBXO6, TARDBP, YWHAQ, PPP6R2, EXOSC10, BAG3, POLR2E, UPF1, SMG1, RBM8A, TTI1, PAN2, TBP, CTNNB1, STOM, RUVBL
Protein Size: 463

Molekulargewicht: 51 kDa

Gen-ID: 10856

NCBI Accession: NM_006666, NP_006657

UniProt: Q9Y230

Pathways: Telomere Maintenance