HNF1B Antikörper (N-Term)

Produktnummer ABIN2779562

Produktdetails anti-HNF1B Antikörper

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LETLPLSPGS GAEPDTKPVF HTLTNGHAKG RLSGDEGSED GDDYDTPPIL

Spezifität: 100 % specific to all three isoforms of HNF1B (61, 58, 45kD).

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HNF1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 399 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HNF1B

Target: HNF1B (HNF1 Homeobox B (HNF1B))

Andere Bezeichnung: HNF1B (HNF1B Produkte)

Synonyme: FJHN antikoerper, HNF-1B antikoerper, HNF1beta antikoerper, HNF2 antikoerper, HPC11 antikoerper, LF-B3 antikoerper, LFB3 antikoerper, MODY5 antikoerper, TCF-2 antikoerper, TCF2 antikoerper, VHNF1 antikoerper, HNF-1b antikoerper, HNF1B antikoerper, AI385728 antikoerper, AI987804 antikoerper, HNF-1Beta antikoerper, Hnf1beta antikoerper, Tcf-2 antikoerper, Tcf2 antikoerper, vHNF1 antikoerper, vHNF-1 antikoerper, chunp6877 antikoerper, hnf1b antikoerper, mst antikoerper, tcf2 antikoerper, vhnf1 antikoerper, lfb3 antikoerper, hnf-1beta antikoerper, hnf1-beta antikoerper, hnf1beta antikoerper, HNF1g antikoerper, wu:fc23f06 antikoerper, HNF1 homeobox B antikoerper, HNF1 homeobox Ba antikoerper, HNF1 homeobox B S homeolog antikoerper, HNF1 homeobox B L homeolog antikoerper, HNF1 homeobox Bb antikoerper, HNF1B antikoerper, Hnf1b antikoerper, hnf1ba antikoerper, hnf1b.S antikoerper, hnf1b.L antikoerper, hnf1bb antikoerper

Hintergrund: Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.
Alias Symbols: FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
Protein Interaction Partner: HIST1H3A, PCBD1, CREBBP, HNF1A, ATF1, CREB1,
Protein Size: 399

Molekulargewicht: 45 kDa

Gen-ID: 6928

NCBI Accession: NM_006481, NP_006472

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation