ZUFSP Antikörper (Middle Region)

Produktnummer ABIN2779538

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ZUFSP in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd und Schwein.

Kurzübersicht für ZUFSP Antikörper (Middle Region) (ABIN2779538)

Target: ZUFSP (Zinc Finger with UFM1-Specific Peptidase Domain (ZUFSP))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZUFSP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZUFSP Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: ZUP1 Antibody - middle region

Sequenz: RQEIEEFQKL QRQYGLDNSG GYKQQQLRNM EIEVNRGRMP PSEFHRRKAD

Homologie: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against C6orf113. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C6orf113

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32274-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ZUFSP

Target: ZUFSP (Zinc Finger with UFM1-Specific Peptidase Domain (ZUFSP))

Andere Bezeichnung: ZUP1

Hintergrund:

Background Information: This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers.

Gene Name: zinc finger containing ubiquitin peptidase 1

Alternative Symbols: DUB, ZUFSP, C6orf113

Protein Name: zinc finger-containing ubiquitin peptidase 1

Molekulargewicht: 66kDa

Gen-ID: 221302

NCBI Accession: NP_659499

UniProt: Q96AP4