SPIC Antikörper (C-Term)

Produktnummer ABIN2779513

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPIC in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Rind (Kuh), Pferd, Ratte, Hund, Meerschweinchen, Kaninchen, Schwein und Zebrafisch (Danio rerio).Es wurde in 1 Publikation zitiert.

Kurzübersicht für SPIC Antikörper (C-Term) (ABIN2779513)

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Reaktivität: Human, Maus, Rind (Kuh), Pferd, Ratte, Hund, Meerschweinchen, Kaninchen, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPIC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPIC Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SPIC Antibody - C-terminal region

Sequenz: EKLAELWGKR KGNRKTMTYQ KMARALRNYG RSGEITKIRR KLTYQFSEAI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SPIC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32232-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SPIC Antikörper (ABIN2779513)

Zhu, Schweitzer, Romer, Sulentic, DeKoter: "Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling." in: European journal of immunology, Vol. 38, Issue 9, pp. 2587-99, (2008) (PubMed).

Details zu SPIC

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Andere Bezeichnung: SPIC

Hintergrund:

Background Information: SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC Regulates VCAM1 gene expression.

Gene Name: Spi-C transcription factor (Spi-1/PU.1 related)

Alternative Symbols: SPI-C

Protein Name: Transcription factor Spi-C

Molekulargewicht: 29kDa

Gen-ID: 121599

NCBI Accession: NP_689536

UniProt: Q8N5J4