SPIC Antikörper (C-Term)
Kurzübersicht für SPIC Antikörper (C-Term) (ABIN2779513)
Target
Alle SPIC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Sequenz
- EKLAELWGKR KGNRKTMTYQ KMARALRNYG RSGEITKIRR KLTYQFSEAI
-
Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against SPIC. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 248 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling." in: European journal of immunology, Vol. 38, Issue 9, pp. 2587-99, (2008) (PubMed).
-
: "Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling." in: European journal of immunology, Vol. 38, Issue 9, pp. 2587-99, (2008) (PubMed).
-
- SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))
-
Andere Bezeichnung
- SPIC
-
Hintergrund
-
SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC Regulates VCAM1 gene expression.
Alias Symbols: MGC40611, SPI-C
Protein Interaction Partner: APP,
Protein Size: 248 -
Molekulargewicht
- 29 kDa
-
Gen-ID
- 121599
-
NCBI Accession
- NM_152323, NP_689536
-
UniProt
- Q8N5J4
Target
-