GSC Antikörper (N-Term)

Produktnummer ABIN2779490

Dieses Anti-GSC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GSC in WB und IHC. Geeignet für Human, Ratte, Maus, Rind (Kuh), Hund und Schwein. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für GSC Antikörper (N-Term) (ABIN2779490)

Target: GSC (Goosecoid Homeobox (GSC))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GSC Antikörper

Bindungsspezifität: N-Term

Sequenz: FPALHGDSLY GASGGASSDY GAFYPRPVAP GGAGLPAAVS GSRLGYNNYF

Homologie: Cow: 86%, Dog: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against GSC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 257 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GSC Antikörper (ABIN2779490)

Behl, Hsieh, Shafer, Mundy, Rice, Boyd, Freedman, Hunter, Jarema, Padilla, Tice: "Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity." in: Neurotoxicology and teratology, Vol. 52, Issue Pt B, pp. 181-93, (2015) (PubMed).

Details zu GSC

Target: GSC (Goosecoid Homeobox (GSC))

Andere Bezeichnung: GSC

Hintergrund: GSC regulates chordin (CHRD). GSC may play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis.This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.
Alias Symbols: -
Protein Interaction Partner: SMAD3, SMAD1, SMAD2, FOXA2,
Protein Size: 257

Molekulargewicht: 28 kDa

Gen-ID: 145258

NCBI Accession: NM_173849, NP_776248

UniProt: P56915