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LMX1A Antikörper (Middle Region)

LMX1A Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779408
  • Target Alle LMX1A Antikörper anzeigen
    LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
    Bindungsspezifität
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 24
    • 18
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen
    Wirt
    • 27
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    Dieser LMX1A Antikörper ist unkonjugiert
    Applikation
    • 22
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    QNQRAKMKKL ARRQQQQQQD QQNTQRLSSA QTNGGGSAGM EGIMNPYTAL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against LMX1A. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human LMX1A
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 382 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))
    Andere Bezeichnung
    LMX1A (LMX1A Produkte)
    Synonyme
    Lmx1.1 antikoerper, dr antikoerper, dreher antikoerper, sst antikoerper, LMX1 antikoerper, LMX1.1 antikoerper, si:ch211-260g14.3 antikoerper, LIM homeobox transcription factor 1 alpha antikoerper, LIM homeobox transcription factor 1, alpha antikoerper, Lmx1a antikoerper, LMX1A antikoerper, lmx1a antikoerper
    Hintergrund
    Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin. Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-199 AL160058.8 14249-14447 c 200-2447 AK127724.1 362-2609 2448-3382 AL390730.12 9415-10349 c
    Alias Symbols: LMX-1, LMX1, LMX1.1, MGC87616
    Protein Interaction Partner: LDB1, BMPR2, ISL1, LHX3, LMX1A, TCF3,
    Protein Size: 382
    Molekulargewicht
    43 kDa
    Gen-ID
    4009
    NCBI Accession
    NM_177398, NP_796372
    UniProt
    Q8TE12
    Pathways
    Dopaminergic Neurogenesis
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