TRIM23 Antikörper (N-Term)

Produktnummer ABIN2779407

Der Kaninchen Polyklonal anti-TRIM23 Antikörper (ABIN2779407) detektiert spezifisch TRIM23 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen und Rind (Kuh).

Kurzübersicht für TRIM23 Antikörper (N-Term) (ABIN2779407)

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRIM23 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TRIM23 Antibody - N-terminal region

Sequenz: CPFDRQVTDL GDSGVWGLKK NFALLELLER LQNGPIGQYG AAEESIGISG

Homologie: Cow: 90%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Rabbit: 85%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIM23. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM23

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114639

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIM23

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Andere Bezeichnung: TRIM23

Hintergrund:

Background Information: TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.

Gene Name: Tripartite motif containing 23

Alternative Symbols: ARD1, ARFD1, RNF46

Protein Name: E3 ubiquitin-protein ligase TRIM23

Molekulargewicht: 64kDa

Gen-ID: 373

NCBI Accession: NP_001647

UniProt: P36406