CCBP2 Antikörper (N-Term)

Produktnummer ABIN2779383

Der Kaninchen Polyklonal Anti-CCBP2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, CCBP2 in Proben von Human und Kaninchen zu detektieren.

Kurzübersicht für CCBP2 Antikörper (N-Term) (ABIN2779383)

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CCBP2 Antikörper

Bindungsspezifität: N-Term

Sequenz: MAATASPQPL ATEDADSENS SFYYYDYLDE VAFMLCRKDA VVSFGKVFLP

Homologie: Human: 100%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CCBP2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCBP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 384 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CCBP2

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Andere Bezeichnung: CCBP2

Hintergrund: CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown.This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
Alias Symbols: CCR10, CCR9, CMKBR9, D6, MGC126678, MGC138250, hD6, CCBP2
Protein Interaction Partner: APP, CCL3L3, CCL28, CCL27, CCL21, CCL25, CCL8, CCL19, CCL14, CCL13, CCL11, CCL5, CCL4, CCL3, CCL7, CCL2,
Protein Size: 384

Molekulargewicht: 43 kDa

Gen-ID: 1238

NCBI Accession: NM_001296, NP_001287

UniProt: O00590