DYRK3 Antikörper (N-Term)

Produktnummer ABIN2779363

Der Kaninchen Polyklonal Anti-DYRK3-Antikörper wurde für WB validiert. Er ist geeignet, DYRK3 in Proben von Human, Ratte, Meerschweinchen und Saccharomyces cerevisiae zu detektieren.

Kurzübersicht für DYRK3 Antikörper (N-Term) (ABIN2779363)

Target: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Reaktivität: Human, Ratte, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYRK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DYRK3 Antikörper

Bindungsspezifität: N-Term

Sequenz: EPPPPRRLNM TTEQFTGDHT QHFLDGGEMK VEQLFQEFGN RKSNTIQSDG

Homologie: Guinea Pig: 83%, Human: 100%, Rat: 90%, Yeast: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against DYRK3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DYRK3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 568 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DYRK3

Target: DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))

Andere Bezeichnung: DYRK3

Hintergrund: This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DYRK5, RED, REDK, hYAK3-2
Protein Interaction Partner: DYRK3, SORL1, FBXO25, PRNP, NEDD4L,
Protein Size: 568

Molekulargewicht: 64 kDa

Gen-ID: 8444

NCBI Accession: NM_001004023, NP_001004023

UniProt: D3DT79

Pathways: Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha