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CLK4 Antikörper (N-Term)

CLK4 Reaktivität: Maus, Human, Kaninchen, Hund, Meerschweinchen, Rind (Kuh), Pferd, Ratte, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779361
  • Target Alle CLK4 Antikörper anzeigen
    CLK4 (CDC-Like Kinase 4 (CLK4))
    Bindungsspezifität
    • 9
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 30
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus, Human, Kaninchen, Hund, Meerschweinchen, Rind (Kuh), Pferd, Ratte, Saccharomyces cerevisiae
    Wirt
    • 31
    • 1
    Kaninchen
    Klonalität
    • 32
    Polyklonal
    Konjugat
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CLK4 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 19
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    RSRRSSPKRK RNRHCSSHQS RSKSHRRKRS RSIEDDEEGH LICQSGDVLR
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 91%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CLK4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4
    Top Product
    Discover our top product CLK4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 481 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Eisenreich, Zakrzewicz, Huber, Thierbach, Pepke, Goldin-Lang, Schultheiss, Pries, Rauch: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." in: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).

  • Target
    CLK4 (CDC-Like Kinase 4 (CLK4))
    Andere Bezeichnung
    CLK4 (CLK4 Produkte)
    Synonyme
    AI987988 antikoerper, C85119 antikoerper, zgc:112975 antikoerper, CDC like kinase 4 antikoerper, CDC-like kinase 4 antikoerper, CDC-like kinase 4b antikoerper, CLK4 antikoerper, Clk4 antikoerper, clk4b antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
    Alias Symbols: DKFZp686A20267
    Protein Interaction Partner: KPNA1, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, CLK4, SRRM2, AHCYL2, SUB1, RASA4, SRPK1, RNF181, CLASRP, UBL5, HSPB2,
    Protein Size: 481
    Molekulargewicht
    57 kDa
    Gen-ID
    57396
    NCBI Accession
    NM_020666, NP_065717
    UniProt
    Q9HAZ1
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