ILK Antikörper (C-Term)

Produktnummer ABIN2779334

Der Kaninchen Polyklonal Anti-ILK-Antikörper wurde für WB validiert. Er ist geeignet, ILK in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Ziege, Meerschweinchen, Pferd, Kaninchen und Schaf zu detektieren.

Kurzübersicht für ILK Antikörper (C-Term) (ABIN2779334)

Target: ILK (Integrin-Linked Kinase (ILK))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Ziege, Meerschweinchen, Pferd, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ILK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ILK Antikörper

Bindungsspezifität: C-Term

Sequenz: MKVALEGLRP TIPPGISPHV CKLMKICMNE DPAKRPKFDM IVPILEKMQD

Homologie: Cow: 100%, Dog: 100%, Goat: 82%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ILK. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ILK

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ILK

Target: ILK (Integrin-Linked Kinase (ILK))

Andere Bezeichnung: ILK

Hintergrund: Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: ILK-2, P59
Protein Interaction Partner: UBC, TRIM27, PARVG, PARVA, RICTOR, ITGB1, MTOR, AKT1, FKBP5, HSPH1, FAF1, CARM1, UGP2, PPAT, FBXO6, ACACA, LIMS2, RHOT1, FANCI, ATAD3A, HEATR1, CLN6, TRAFD1, ZNF568, TIMM50, RHOT2, TRABD, LPCAT1, VKORC1, RPL13, ABCE1, RBBP7, RAF1, SDF4, SEC61A1, PARVB, AK
Protein Size: 452

Molekulargewicht: 49 kDa

Gen-ID: 3611

NCBI Accession: NM_004517, NP_004508

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration