Crk Antikörper (C-Term)
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- Target Alle Crk (CRK) Antikörper anzeigen
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Crk Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- IPVPYVEKYR PASASVSALI GGNQEGSHPQ PLGGPEPGPY AQPSVNTPLP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CRK. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product CRK Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 304 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
- Andere Bezeichnung
- CRK (CRK Produkte)
- Synonyme
- CG1587 antikoerper, CRK antikoerper, D-CRK antikoerper, D-Crk antikoerper, DCrk antikoerper, Dcrk antikoerper, Dmel\\CG1587 antikoerper, crk antikoerper, dCRK antikoerper, dCrk antikoerper, fb34h10 antikoerper, fc05a01 antikoerper, fi19g05 antikoerper, wu:fb34h10 antikoerper, wu:fc05a01 antikoerper, wu:fc54a04 antikoerper, wu:fi19g05 antikoerper, zgc:100936 antikoerper, CRKII antikoerper, p38 antikoerper, Crko antikoerper, crk2 antikoerper, crkII antikoerper, v-crk antikoerper, P38C-CRK antikoerper, Crk-I antikoerper, Crk-II antikoerper, Crk-III antikoerper, Crk3 antikoerper, CrkIII antikoerper, c-Crk antikoerper, Crk oncogene antikoerper, v-crk avian sarcoma virus CT10 oncogene homolog antikoerper, CRK proto-oncogene, adaptor protein antikoerper, v-crk avian sarcoma virus CT10 oncogene homolog L homeolog antikoerper, v-crk sarcoma virus CT10 oncogene homolog antikoerper, Crk antikoerper, crk antikoerper, CRK antikoerper, crk.L antikoerper
- Hintergrund
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This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
Alias Symbols: CRKII, p38
Protein Interaction Partner: FAM154A, HUWE1, ABL2, ABL1, SPRR2A, MET, CBL, BAG3, LMNA, ERBB3, ERBB2, EGFR, PPFIBP2, ATXN1, PTPN4, MAPK4, DOK1, BCAR1, NANS, FUBP1, SPR, HSPB1, DHX9, SERPINH1, ATIC, PIK3R2, PIK3R1, PIK3CD, PIK3CB, PIK3CA, PIK3C2B, SERPINB6, LYZ, KRT19, KRT17, KRT16, KR
Protein Size: 304 - Molekulargewicht
- 34 kDa
- Gen-ID
- 1398
- NCBI Accession
- NM_016823, NP_058431
- UniProt
- P46108
- Pathways
- Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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