L3MBTL2 Antikörper (C-Term)

Produktnummer ABIN182328

Dieser Anti-L3MBTL2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von L3MBTL2 in WB und IHC. Geeignet für Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Meerschweinchen und Kaninchen. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für L3MBTL2 Antikörper (C-Term) (ABIN182328)

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser L3MBTL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-L3MBTL2 Antikörper

Bindungsspezifität: C-Term

Sequenz: EYDQWVDCES PDIYPVGWCE LTGYQLQPPV AAEPATPLKA KEATKKKKKQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 80%, Rabbit: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against L3MBTL2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human L3MBTL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 705 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-L3MBTL2 Antikörper (ABIN182328)

Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, (2004) (PubMed).

Details zu L3MBTL2

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Andere Bezeichnung: L3MBTL2

Hintergrund: L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.
Alias Symbols: H-l(3)mbt-l, L3MBT
Protein Interaction Partner: TRIM42, STAC3, PHF10, TBC1D9B, PAICS, AES, SUMO2, SUMO1, PIAS1, HIST1H4A, HIST1H3A, RNF2, MPP3, PCGF6, RYBP, YAF2, SMARCAD1, HIST4H4, CBX3, HIST3H3, E2F6, Lin54, HDAC3, MEAF6, STAM2, RB1,
Protein Size: 705

Molekulargewicht: 79 kDa

Gen-ID: 83746

NCBI Accession: NM_031488, NP_113676

UniProt: Q969R5