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L3MBTL2 Antikörper (C-Term)

Dieses Anti-L3MBTL2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von L3MBTL2 in WB und IHC. Geeignet für Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Meerschweinchen und Kaninchen. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN2779266

Kurzübersicht für L3MBTL2 Antikörper (C-Term) (ABIN2779266)

Target

Alle L3MBTL2 Antikörper anzeigen
L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Reaktivität

  • 31
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen

Wirt

  • 29
  • 2
Kaninchen

Klonalität

  • 29
  • 2
Polyklonal

Konjugat

  • 22
  • 3
  • 2
  • 2
  • 1
  • 1
Dieser L3MBTL2 Antikörper ist unkonjugiert

Applikation

  • 26
  • 18
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    EYDQWVDCES PDIYPVGWCE LTGYQLQPPV AAEPATPLKA KEATKKKKKQ

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 80%, Rabbit: 100%, Rat: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against L3MBTL2. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human L3MBTL2
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 705 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, (2004) (PubMed).

  • Target

    L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

    Andere Bezeichnung

    L3MBTL2

    Hintergrund

    L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.
    Alias Symbols: H-l(3)mbt-l, L3MBT
    Protein Interaction Partner: TRIM42, STAC3, PHF10, TBC1D9B, PAICS, AES, SUMO2, SUMO1, PIAS1, HIST1H4A, HIST1H3A, RNF2, MPP3, PCGF6, RYBP, YAF2, SMARCAD1, HIST4H4, CBX3, HIST3H3, E2F6, Lin54, HDAC3, MEAF6, STAM2, RB1,
    Protein Size: 705

    Molekulargewicht

    79 kDa

    Gen-ID

    83746

    NCBI Accession

    NM_031488, NP_113676

    UniProt

    Q969R5
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