EEA1 Antikörper (N-Term)

Produktnummer ABIN182326

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EEA1 in WB, IHC und IP. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Pferd, Rind (Kuh) und Meerschweinchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für EEA1 Antikörper (N-Term) (ABIN182326)

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-EEA1 Antikörper

Bindungsspezifität: N-Term

Sequenz: LTENLLKKEQ DYTKLEEKHN EESVSKKNIQ ATLHQKDLDC QQLQSRLSAS

Homologie: Cow: 92%, Dog: 75%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against EEA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EEA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1411 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EEA1 Antikörper (ABIN182326)

Cebrian, Croce, Guerrero, Blanchard, Mayorga: "Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells." in: EMBO reports, Vol. 17, Issue 12, pp. 1753-1765, (2016) (PubMed).

Details zu EEA1

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Andere Bezeichnung: EEA1

Hintergrund: EEA1 is involved in neuronal synaptic vesicle function and axonal transport and growth. EEA1 may undergo calcium-dependent conformational changes that are required for binding to SNAP-25.
Alias Symbols: MST105, ZFYVE2, MSTP105
Protein Interaction Partner: UBC, RNF2, BMI1, CFTR, ERBB2, VCP, EEA1, RAB5A, TNK2, RABEP1, RABGEF1, PDCD6IP, PXK, HDAC6, ZFYVE16, USO1, STX6, RAB22A, STX12, TOM1, RAB5C, MAPK14, RAB5B, IGF1R, NSF,
Protein Size: 1411

Molekulargewicht: 162 kDa

Gen-ID: 8411

NCBI Accession: NM_003566, NP_003557

UniProt: Q15075

Pathways: Toll-Like Receptors Cascades