EEA1 Antikörper (N-Term)

Produktnummer ABIN2779263

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch EEA1 in WB, IHC und IP. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh) und Meerschweinchen.Es wurde in 1 Publikation zitiert.

Kurzübersicht für EEA1 Antikörper (N-Term) (ABIN2779263)

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-EEA1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: EEA1 Antibody - N-terminal region

Sequenz: LTENLLKKEQ DYTKLEEKHN EESVSKKNIQ ATLHQKDLDC QQLQSRLSAS

Homologie: Cow: 92%, Dog: 75%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against EEA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EEA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099412

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EEA1 Antikörper (ABIN2779263)

Cebrian, Croce, Guerrero, Blanchard, Mayorga: "Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells." in: EMBO reports, Vol. 17, Issue 12, pp. 1753-1765, (2016) (PubMed).

Details zu EEA1

Target: EEA1 (Early Endosome Antigen 1 (EEA1))

Andere Bezeichnung: EEA1

Hintergrund:

Background Information: EEA1 is involved in neuronal synaptic vesicle function and axonal transport and growth. EEA1 may undergo calcium-dependent conformational changes that are required for binding to SNAP-25.

Gene Name: Early endosome antigen 1

Alternative Symbols: MST105, ZFYVE2, MSTP105

Protein Name: Early endosome antigen 1

Molekulargewicht: 162kDa

Gen-ID: 8411

NCBI Accession: NP_003557

UniProt: Q15075

Pathways: Toll-Like Receptors Cascades