ZNF496 Antikörper (Middle Region)

Produktnummer ABIN2779244

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ZNF496 in WB. Es zeigt Reaktivität gegenüber Proben von Maus, Human, Ratte, Rind (Kuh), Schaf, Hund, Pferd, Schwein und Kaninchen.

Kurzübersicht für ZNF496 Antikörper (Middle Region) (ABIN2779244)

Target: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Reaktivität: Maus, Human, Ratte, Rind (Kuh), Schaf, Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF496 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZNF496 Antikörper

Bindungsspezifität: Middle Region

Sequenz: QEKPHECSVC GELFSDSEDL DGHLESHEAQ KPYRCGACGK SFRLNSHLLS

Homologie: Cow: 86%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ZNF496. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZNF496

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 587 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZNF496

Target: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Andere Bezeichnung: ZNF496

Hintergrund: ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
Alias Symbols: MGC15548, NIZP1, ZKSCAN17, ZFP496
Protein Interaction Partner: ZKSCAN4, ZSCAN22, ZNF483, ZNF446, ZSCAN12, ZSCAN21, ARR3, Nsd1, SUMO2, UBC, CBX3, TRIM28, NR3C1, POLR3D, ZZZ3, JADE2, RAI1, SSX3, SUPT5H, PPARG,
Protein Size: 587

Molekulargewicht: 67 kDa

Gen-ID: 84838

NCBI Accession: NM_032752, NP_116141

UniProt: Q96IT1