ZNF496 Antikörper (Middle Region)
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- Target Alle ZNF496 Antikörper anzeigen
- ZNF496 (Zinc Finger Protein 496 (ZNF496))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Maus, Human, Ratte, Rind (Kuh), Schaf, Hund, Pferd, Schwein, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZNF496 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- QEKPHECSVC GELFSDSEDL DGHLESHEAQ KPYRCGACGK SFRLNSHLLS
- Homologie
- Cow: 86%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ZNF496. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ZNF496
- Top Product
- Discover our top product ZNF496 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 587 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ZNF496 (Zinc Finger Protein 496 (ZNF496))
- Andere Bezeichnung
- ZNF496 (ZNF496 Produkte)
- Synonyme
- Zkscan17 antikoerper, Znf496 antikoerper, ZNF496 antikoerper, NIZP1 antikoerper, ZFP496 antikoerper, ZKSCAN17 antikoerper, ZSCAN49 antikoerper, BC040205 antikoerper, D130067D09 antikoerper, Nizp1 antikoerper, Zfp496 antikoerper, zinc finger protein 496 antikoerper, zinc finger with KRAB and SCAN domains 17 antikoerper, Zfp496 antikoerper, ZNF496 antikoerper, Zkscan17 antikoerper
- Hintergrund
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ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
Alias Symbols: MGC15548, NIZP1, ZKSCAN17, ZFP496
Protein Interaction Partner: ZKSCAN4, ZSCAN22, ZNF483, ZNF446, ZSCAN12, ZSCAN21, ARR3, Nsd1, SUMO2, UBC, CBX3, TRIM28, NR3C1, POLR3D, ZZZ3, JADE2, RAI1, SSX3, SUPT5H, PPARG,
Protein Size: 587 - Molekulargewicht
- 67 kDa
- Gen-ID
- 84838
- NCBI Accession
- NM_032752, NP_116141
- UniProt
- Q96IT1
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