XRN1 Antikörper (Middle Region)

Produktnummer ABIN2779146

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch XRN1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein, Kaninchen und Saccharomyces cerevisiae.

Kurzübersicht für XRN1 Antikörper (Middle Region) (ABIN2779146)

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-XRN1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LPQEISQVNQ HHKSGFNDNS VKYQQRKHDP HRKFKEECKS PKAECWSQKM

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 79%, Horse: 90%, Human: 100%, Mouse: 86%, Pig: 85%, Rabbit: 100%, Rat: 100%, Yeast: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against XRN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human XRN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1706 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu XRN1

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Andere Bezeichnung: XRN1

Hintergrund: SEP1 (XRN1) localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-67 BX640905.1 1-67 68-5188 AY137776.1 1-5121 5189-5269 BG197321.1 308-388 5270-10092 AC023508.16 31718-36540 c
Alias Symbols: DKFZp434P0721, DKFZp686B22225, DKFZp686F19113, FLJ41903, SEP1
Protein Interaction Partner: ZFP36, UBC, RPA3, RPA2, RPA1, BMI1, HECW2, HERC2P4, RNF187, B3GALT6, EXOSC6, C1orf85, VWA5B2, MFSD5, PRADC1, ANGPTL6, PLEKHG2, SPATA20, C1GALT1, DCP1A, HEATR1, NDUFA13, EXOSC1, DPP7, RBMX, MTCH2, TMEM50A, CD97, ATP5G2, SNHG1, LINC01541, DCP1B, SRRM2, SKIV
Protein Size: 1706

Molekulargewicht: 194 kDa

Gen-ID: 54464

NCBI Accession: NM_019001, NP_061874

UniProt: Q8IZH2