MATR3 Antikörper (N-Term)

Produktnummer ABIN2779141

Dieses Anti-MATR3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MATR3 in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen und Kaninchen. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für MATR3 Antikörper (N-Term) (ABIN2779141)

Target: MATR3 (Matrin 3 (MATR3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MATR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MATR3 Antikörper

Bindungsspezifität: N-Term

Sequenz: MSKSFQQSSL SRDSQGHGRD LSAAGIGLLA AATQSLSMPA SLGRMNQGTA

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MATR3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MATR3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 847 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MATR3 Antikörper (ABIN2779141)

Kula, Gharu, Marcello: "HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3." in: Virology, Vol. 435, Issue 2, pp. 329-40, (2012) (PubMed).

Kula, Guerra, Knezevich, Kleva, Myers, Marcello: "Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function." in: Retrovirology, Vol. 8, pp. 60, (2011) (PubMed).

Valencia, Ju, Liu: "Matrin 3 is a Ca2+/calmodulin-binding protein cleaved by caspases." in: Biochemical and biophysical research communications, Vol. 361, Issue 2, pp. 281-6, (2007) (PubMed).

Details zu MATR3

Target: MATR3 (Matrin 3 (MATR3))

Andere Bezeichnung: MATR3

Hintergrund: MATR3 is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network.The protein encoded by this gene is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: MPD2, VCPDM
Protein Interaction Partner: RASD1, MATR3, UBC, HNRNPK, CEP250, AURKA, SUMO2, SUMO3, STAU1, LGR4, SUMO1, MDM2, RPA3, RPA2, RPA1, ERG, WWOX, EED, rev, PARK2, TARDBP, PAN2, ITGA4, IFIT2, FN1, MAP1LC3A, PTBP2, vpr, MAGOH, EIF4A3, PRKCDBP, NAA15, IARS2, SMU1, SARS2, STOML2, RRP7A, MYOF,
Protein Size: 847

Molekulargewicht: 93 kDa

Gen-ID: 9782

NCBI Accession: NM_018834, NP_061322

UniProt: P43243