OAS2 Antikörper (Middle Region)

Produktnummer ABIN2779107

Der Kaninchen Polyklonal anti-OAS2 Antikörper (ABIN2779107) detektiert spezifisch OAS2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Schwein, Kaninchen, Hund und Rind (Kuh).

Kurzübersicht für OAS2 Antikörper (Middle Region) (ABIN2779107)

Target: OAS2 (2'-5' Oligoadenylate Synthetase 2 (OAS2))

Reaktivität: Human, Schwein, Kaninchen, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-OAS2 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: OAS2 Antibody - middle region

Sequenz: AKGTALKTGS DADLVVFHNS LKSYTSQKNE RHKIVKEIHE QLKAFWREKE

Homologie: Cow: 92%, Dog: 92%, Human: 100%, Pig: 100%, Rabbit: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against OAS2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human OAS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40852-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu OAS2

Target: OAS2 (2'-5' Oligoadenylate Synthetase 2 (OAS2))

Andere Bezeichnung: OAS2

Hintergrund:

Background Information: OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Name: 2'-5'-oligoadenylate synthetase 2, 69/71 kDa

Alternative Symbols: MGC78578

Protein Name: 2'-5'-oligoadenylate synthase 2

Molekulargewicht: 82kDa

Gen-ID: 4939

NCBI Accession: NP_058197

UniProt: P29728

Pathways: Hepatitis C