HSD17B11 Antikörper (Middle Region)

Produktnummer ABIN2779101

Produktdetails anti-HSD17B11 Antikörper

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IYSAAKKVKE EVGDVSILVN NAGVVYTADL FATQDPQIEK TFEVNVLAHF

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Hsd17b11. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 298 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HSD17B11

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Andere Bezeichnung: Hsd17b11 (HSD17B11 Produkte)

Synonyme: 17BHSD11 antikoerper, DHRS8 antikoerper, PAN1B antikoerper, RETSDR2 antikoerper, SDR16C2 antikoerper, Dhrs8 antikoerper, HSD17B13 antikoerper, MGC84756 antikoerper, HSD17B11 antikoerper, Pan1b antikoerper, SDR2 antikoerper, retSDR2 antikoerper, 17-beta-HSD 11 antikoerper, 17-beta-HSD XI antikoerper, 17bHSD11 antikoerper, 17betaHSD11 antikoerper, 17betaHSDXI antikoerper, hydroxysteroid 17-beta dehydrogenase 11 antikoerper, hydroxysteroid (17-beta) dehydrogenase 11 antikoerper, hydroxysteroid (17-beta) dehydrogenase 11 L homeolog antikoerper, estradiol 17-beta-dehydrogenase 11 antikoerper, HSD17B11 antikoerper, Hsd17b11 antikoerper, hsd17b11.L antikoerper, hsd17b11 antikoerper, LOC100348005 antikoerper, LOC100520923 antikoerper

Hintergrund: Hsd17b11 can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. Hsd17b11 may act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. It has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
Alias Symbols: Dhrs8, Pan1b, SDR2, retSDR2
Protein Interaction Partner: Eed,
Protein Size: 298

Molekulargewicht: 33 kDa

Gen-ID: 114664

NCBI Accession: NM_053262, NP_444492

UniProt: Q9EQ06