Pre-mRNA Branch Site Protein p14 (SF3B14) (Middle Region) Antikörper

Produktnummer ABIN2779093

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Pre-mRNA Branch Site Protein p14 Antikörper wird verwendet zum Nachweis von Pre-mRNA Branch Site Protein p14 in Proben von Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für Pre-mRNA Branch Site Protein p14 (SF3B14) (Middle Region) Antikörper (ABIN2779093)

Target: Pre-mRNA Branch Site Protein p14 (SF3B14)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: Middle Region

Verwendungszweck: SF3B6 Antibody - middle region

Sequenz: HLSGFNVCNR YLVVLYYNAN RAFQKMDTKK KEEQLKLLKE KYGINTDPPK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SF3B14. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SF3B14

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108839

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Antigendetails

Target: Pre-mRNA Branch Site Protein p14 (SF3B14)

Andere Bezeichnung: SF3B6

Hintergrund:

Background Information: This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

Gene Name: splicing factor 3b subunit 6

Alternative Symbols: P14, Ht006, SAP14, SAP14a, SF3B14, CGI-110, HSPC175, SF3B14a

Protein Name: splicing factor 3B subunit 6

Molekulargewicht: 14kDa

Gen-ID: 51639

NCBI Accession: NP_057131

UniProt: Q7RTV0