PUM2 Antikörper (N-Term)

Produktnummer ABIN2779083

Produktdetails anti-PUM2 Antikörper

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PUM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MNHDFQALAL ESRGMGELLP TKKFWEPDDS TKDGQKGIFL GDDEWRETAW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PUM2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PUM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1064 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PUM2

Target: PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))

Andere Bezeichnung: PUM2 (PUM2 Produkte)

Synonyme: pum-2 antikoerper, 5730503J23Rik antikoerper, Pumm2 antikoerper, mKIAA0235 antikoerper, PUMH2 antikoerper, PUML2 antikoerper, pumilio RNA binding family member 2 antikoerper, pumilio RNA-binding family member 2 antikoerper, pum2 antikoerper, Pum2 antikoerper, PUM2 antikoerper

Hintergrund: PUM2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
Alias Symbols: FLJ36528, KIAA0235, MGC138251, MGC138253, PUMH2, PUML2
Protein Interaction Partner: NANOS3, BMI1, gag-pol, UBC, DAZL, DAZ1, ELAVL1, MED4, AURKA, NANOS1, DAZ2, DAZ4, PUM2, MED23, IKZF5,
Protein Size: 1064

Molekulargewicht: 114 kDa

Gen-ID: 23369

NCBI Accession: NM_015317, NP_056132

UniProt: B3KSL0

Pathways: Ribonucleoprotein Complex Subunit Organization