EXOSC2 Antikörper (Middle Region)

Produktnummer ABIN2779056

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch EXOSC2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio) und wurde in 1 Publikation erwähnt.

Kurzübersicht für EXOSC2 Antikörper (Middle Region) (ABIN2779056)

Target: EXOSC2 (Exosome Component 2 (EXOSC2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOSC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EXOSC2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AEVQAVFSDG AVSLHTRSLK YGKLGQGVLV QVSPSLVKRQ KTHFHDLPCG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EXOSC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EXOSC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 293 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EXOSC2 Antikörper (ABIN2779056)

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Details zu EXOSC2

Target: EXOSC2 (Exosome Component 2 (EXOSC2))

Andere Bezeichnung: EXOSC2

Hintergrund: EXOSC2 belongs to the exosome, a RNA-processing complex, which is at least involved in the 3' processing of the 7S pre-rRNA to the mature 5.8S rRNA. It exhibits a 3'-5' exoribonuclease activity.
Alias Symbols: RRP4, Rrp4p, hRrp4p, p7
Protein Interaction Partner: GPX1, ST6GALNAC1, MRPL48, EXOSC7, RNF8, GALNT13, ZNF408, AICDA, METTL22, UBC, UPF1, MDC1, BARD1, EXOSC5, EXOSC4, EXOSC3, DEK, RAN, EXOSC9, DIS3L, DIS3, UBD, CAND1, HDGF, MEPCE, SKIV2L2, EXOSC6, KHSRP, MPP6, EXOSC8, UPF3A, UPF2,
Protein Size: 293

Molekulargewicht: 32 kDa

Gen-ID: 23404

NCBI Accession: NM_014285, NP_055100

UniProt: Q13868

Pathways: SARS-CoV-2 Protein Interaktom