EWSR1 Antikörper (Middle Region)

Produktnummer ABIN2779045

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EWSR1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für EWSR1 Antikörper (Middle Region) (ABIN2779045)

Target: EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EWSR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-EWSR1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: QPSSYGQQSS YGQQSSYGQQ PPTSYPPQTG SYSQAPSQYS QQSSSYGQQS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EWSR1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EWSR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 656 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EWSR1

Target: EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

Andere Bezeichnung: EWSR1

Hintergrund: EWSR1 is a putative RNA binding protein. Mutations in this gene, specifically a t(11,22)(q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products.This gene encodes a putative RNA binding protein. Mutations in this gene, specifically a t(11,22)(q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products.
Alias Symbols: EWS, bK984G1.4
Protein Interaction Partner: SSBP3, SEC24A, TFG, SEC24D, PEF1, MAPK1IP1L, ATPAF2, TRAF2, TRAF1, PLSCR1, PRR13, UBC, RPA3, RPA2, RPA1, EZH2, SUZ12, RNF2, BMI1, rev, ITCH, WBP4, PRMT1, CCDC7, YY1AP1, MRPS18B, UBD, CD81, RIOK2, NONO, ITGB5, ITGA4, FUS, FN1, EWSR1, EPAS1, EP300, HNRNPUL1
Protein Size: 656

Molekulargewicht: 68 kDa

Gen-ID: 2130

NCBI Accession: NM_005243, NP_005234

UniProt: Q01844