SMNDC1 Antikörper (Middle Region)

Produktnummer ABIN2778955

Der Kaninchen Polyklonal Anti-SMNDC1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SMNDC1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Ziege, Pferd und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für SMNDC1 Antikörper (Middle Region) (ABIN2778955)

Target: SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Ziege, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMNDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SMNDC1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: QFNNRAYSKN KKGQVKRSIF ASPESVTGKV GVGTCGIADK PMTQYQDTSK

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SMNDC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMNDC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 238 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMNDC1

Target: SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))

Andere Bezeichnung: SMNDC1

Hintergrund: This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
Alias Symbols: SMNR, SPF30
Protein Interaction Partner: UBC, PRPF3, SF3B5, SND1, CUL3, SF3A2, ELAVL1, HIST3H3, mad2, KPNB1, SNRNP200, SNRPB, CDK5RAP3, PPAN, TSR1, RNMTL1, SF3B1, SF3B3, SF3B2, SF3A3, SF3B4, DDX21, RUVBL1, RPL3, FDFT1, EWSR1,
Protein Size: 238

Molekulargewicht: 27 kDa

Gen-ID: 10285

NCBI Accession: NM_005871, NP_005862

UniProt: O75940