KARS Antikörper (C-Term)

Produktnummer ABIN2778941

Der Kaninchen Polyklonal Anti-KARS-Antikörper wurde für WB und IHC validiert. Er ist geeignet, KARS in Proben von Human, Maus, Ratte, Meerschweinchen, Pferd, Schwein, Kaninchen und Rind (Kuh) zu detektieren.

Kurzübersicht für KARS Antikörper (C-Term) (ABIN2778941)

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Schwein, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-KARS Antikörper

Bindungsspezifität: C-Term

Sequenz: GMGIDRVAMF LTDSNNIKEV LLFPAMKPED KKENVATTDT LESTTVGTSV

Homologie: Cow: 92%, Guinea Pig: 85%, Horse: 88%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against KARS. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KARS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 597 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KARS

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Andere Bezeichnung: KARS

Hintergrund: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Alias Symbols: KRS, KARS2, CMTRIB
Protein Interaction Partner: AIMP2, SUMO2, SUMO3, MDM2, UBC, SUMO1, NEDD8, STAT1, SSB, RPL21, RPL19, RPL17, NAP1L4, HSPA4, GPX1, CARS, APEH, CAND1, RANBP6, RPL36, JMJD6, NUDC, IPO7, AIMP1, SH3RF2, FBXO6, vpr, MSK1, gag, FN1, TRMT1, MRPS18B, UBE2S, CCT8, EEF1E1, VBP1, UBA1, RARS, QARS
Protein Size: 597

Molekulargewicht: 66 kDa

Gen-ID: 3735

NCBI Accession: NM_005548, NP_005539

UniProt: Q15046