RBM8A Antikörper (N-Term)

Produktnummer ABIN2778929

Der Kaninchen Polyklonal Anti-RBM8A-Antikörper wurde für WB und IHC validiert. Er ist geeignet, RBM8A in Proben von Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Schwein und Kaninchen zu detektieren.

Kurzübersicht für RBM8A Antikörper (N-Term) (ABIN2778929)

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RBM8A Antikörper

Bindungsspezifität: N-Term

Sequenz: LHEAGGEDFA MDEDGDESIH KLKEKAKKRK GRGFGSEEGS RARMREDYDS

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 82%, Rabbit: 82%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RBM8A. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RBM8A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 174 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RBM8A

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Andere Bezeichnung: RBM8A

Hintergrund: RBM8A is a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B, it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.
Alias Symbols: Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014
Protein Interaction Partner: MAGOHB, MAGOH, UBC, SUZ12, RNF2, PARK2, SRPK2, SRPK1, FBXO25, tat, UPF3B, SMG9, SMG8, PABPC1, UPF2, SMG5, SMG1, RUVBL2, RBM8A, SMG7, EIF4A3, TTI1, RUVBL1, UPF1, NCBP2, TOE1, SF3B2, RPS16, RPL11, HBB, GSPT1, ZFP36L1, UNC119B, SLIRP, LSM2, CIAPIN1, TFCP2L1,
Protein Size: 174

Molekulargewicht: 19 kDa

Gen-ID: 9939

NCBI Accession: NM_005105, NP_005096

UniProt: Q9Y5S9