RBM8A Antikörper (N-Term)

Produktnummer ABIN2778928

Produktdetails anti-RBM8A Antikörper

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EDFAMDEDGD ESIHKLKEKA KKRKGRGFGS EEGSRARMRE DYDSVEQDGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Rbm8a. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Rbm8a

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 174 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RBM8A

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Andere Bezeichnung: Rbm8a (RBM8A Produkte)

Synonyme: BOV-1A antikoerper, BOV-1B antikoerper, BOV-1C antikoerper, C1DELq21.1 antikoerper, DEL1q21.1 antikoerper, MDS014 antikoerper, RBM8 antikoerper, RBM8B antikoerper, TAR antikoerper, Y14 antikoerper, ZNRP antikoerper, ZRNP1 antikoerper, 2310057C03Rik antikoerper, AA673428 antikoerper, Rbm8 antikoerper, RBM8A antikoerper, rbm8 antikoerper, rbm8a antikoerper, rnp-5 antikoerper, fb34f03 antikoerper, wu:fb34f03 antikoerper, zgc:110525 antikoerper, rbm8-A antikoerper, rbm8a-A antikoerper, rbm8-B antikoerper, RNA binding motif protein 8A antikoerper, RNA binding motif protein 8a antikoerper, RNA binding motif protein 8A S homeolog antikoerper, RNA binding motif protein 8A L homeolog antikoerper, RBM8A antikoerper, Rbm8a antikoerper, rbm8a antikoerper, rbm8a.S antikoerper, rbm8a.L antikoerper

Hintergrund: Rbm8a is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The heterodimer MAGOH-RBM8A interacts with PYM that function to enhance the translation of EJC-bearing spliced mRNAs by recruiting them to the ribosomal 48S preinitiation complex.
Alias Symbols: Rbm8
Protein Interaction Partner: Stau2,
Protein Size: 174

Molekulargewicht: 19 kDa

Gen-ID: 295284

NCBI Accession: XM_215637, XP_215637

UniProt: Q27W01