HNRNPF Antikörper (C-Term)

Produktnummer ABIN2778920

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HNRNPF in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund und Pferd und wurde in 1 Publikation erwähnt.

Kurzübersicht für HNRNPF Antikörper (C-Term) (ABIN2778920)

Target: HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HNRNPF Antikörper

Bindungsspezifität: C-Term

Sequenz: LNSTTGASNG AYSSQVMQGM GVSAAQATYS GLESQSVSGC YGAGYSGQNS

Homologie: Cow: 91%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRPF. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 415 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNRNPF Antikörper (ABIN2778920)

White, Gonsior, Bauer, Krämer-Albers, Luhmann, Trotter: "Heterogeneous nuclear ribonucleoprotein (hnRNP) F is a novel component of oligodendroglial RNA transport granules contributing to regulation of myelin basic protein (MBP) synthesis." in: The Journal of biological chemistry, Vol. 287, Issue 3, pp. 1742-54, (2012) (PubMed).

Details zu HNRNPF

Target: HNRNPF (Heterogeneous Nuclear Ribonucleoprotein F (HNRNPF))

Andere Bezeichnung: HNRPF

Hintergrund: HNRPF belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH.
Alias Symbols: HNRPF, mcs94-1, OK/SW-cl.23
Protein Interaction Partner: HSFY1, C1orf94, CCDC33, EIF4ENIF1, RBFOX2, IKZF3, HNRNPUL1, HNRNPM, FUS, TFG, DZIP3, UBC, AES, NEDD1, CEP250, SUMO2, SUMO3, TP53, CDC20, STAU1, IVNS1ABP, SUMO1, NEDD8, MDM2, WWOX, RPA3, RPA2, RPA1, ERG, EED, rev, PRPF40A, OSGEP, ABCF3, DNAAF5, PPME1, PPP1
Protein Size: 415

Molekulargewicht: 46 kDa

Gen-ID: 3185

NCBI Accession: NM_004966, NP_004957

UniProt: P52597