CPNE1 Antikörper (Middle Region)

Produktnummer ABIN2778879

Der Kaninchen Polyklonal Anti-CPNE1-Antikörper wurde für WB validiert. Er ist geeignet, CPNE1 in Proben von Human, Rind (Kuh), Hund, Pferd, Maus, Kaninchen, Ratte, Schaf, Meerschweinchen, Zebrafisch (Danio rerio) und Schwein zu detektieren.

Kurzübersicht für CPNE1 Antikörper (Middle Region) (ABIN2778879)

Target: CPNE1 (Copine I (CPNE1))

Reaktivität: Human, Rind (Kuh), Hund, Pferd, Maus, Kaninchen, Ratte, Schaf, Meerschweinchen, Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPNE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CPNE1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: VQCSDYDSDG SHDLIGTFHT SLAQLQAVPA EFECIHPEKQ QKKKSYKNSG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 91%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CPNE1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CPNE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 537 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CPNE1

Target: CPNE1 (Copine I (CPNE1))

Andere Bezeichnung: CPNE1

Hintergrund: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. CPNE1 is a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Sequence analysis identified multiple alternatively spliced variants in the 5' UTR. All variants encode the same protein.
Alias Symbols: COPN1, CPN1, MGC1142
Protein Interaction Partner: UBC, BAG3, BUB3, STK3, FN1, LIG4, TIMM13, TTLL12, ST13, PYGB, ARRB2, SUMO2, UIMC1, HNRNPH1, UBE2O, WTAP, MYCBP, PITPNM2, CCDC22, BCOR, CPNE4, CPNE1, UBE2M, PDCD6, PPP5C, SPTBN1, RDX, MAP2K1, SKIL, ACTB, Cdc42bpb, Etl4, Cenpf, Mycbp2, Alg2, Nono,
Protein Size: 537

Molekulargewicht: 59 kDa

Gen-ID: 8904

NCBI Accession: NM_003915, NP_003906

UniProt: Q99829