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PSMA6 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PSMA6 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Ziege, Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio) und Saccharomyces cerevisiae.
Produktnummer ABIN2778812

Kurzübersicht für PSMA6 Antikörper (N-Term) (ABIN2778812)

Target

Alle PSMA6 Antikörper anzeigen
PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Reaktivität

  • 46
  • 36
  • 31
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Ziege, Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt

  • 40
  • 6
Kaninchen

Klonalität

  • 41
  • 5
Polyklonal

Konjugat

  • 25
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PSMA6 Antikörper ist unkonjugiert

Applikation

  • 40
  • 13
  • 11
  • 10
  • 9
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    EYAFKAINQG GLTSVAVRGK DCAVIVTQKK VPDKLLDSST VTHLFKITEN

    Homologie

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against PSMA6. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human PSMA6
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 246 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

    Andere Bezeichnung

    PSMA6

    Hintergrund

    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA6 is a member of the peptidase T1A family, which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: IOTA, MGC22756, MGC2333, MGC23846, PROS27, p27K
    Protein Interaction Partner: UBC, RNF170, LIMD2, C19orf57, TRIM39, ZBTB44, CADM1, HUWE1, PSMA3, RTP5, KRTAP4-2, AURKA, PSMD14, MDM2, PSMA5, PSMG3, PSMG2, PSMG1, RNF2, PSMB8, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMB2, PSMB1, PSMA7, PSMA4, PSMA1, HNRNPA2B1, PYCRL, RPP38, RPP30, CAST, PS
    Protein Size: 246

    Molekulargewicht

    27 kDa

    Gen-ID

    5687

    NCBI Accession

    NM_002791, NP_002782

    UniProt

    P60900

    Pathways

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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